Which BME should I use for the Tube Formation assay?
FAQ from Trevigen
Reduced Growth Factor BME (RGF BME) is generally used for testing compounds that promote angiogenesis because formation of capillary-like structures (tubes) is significantly less, compared to complete basement membrane matrix (Normal BME). Trevigen’s Tube Formation Kit includes a qualified production lot of RGF BME that exhibits reduced background tube formation in the absence of angiogenic factors.