CROSS-LINKERS

See also: Protein modifyers - Buffers - Labeling reagents (biotin)

1

2

3

4

5

6

7

8

9

10

11

12

13

Photo-reactive cross-linkers with other reactivities (page10...page13)

ABH

ASBA

ABH

UP87750A

100mg

ASBA

UP66329A

100mg

50mg

Photoreactive, carbohydrate selective cross-linker

• Hydrazide reacts with cis-diol of carbohydrates or proteins

• Aryl azide reacts upon UV photolysis with other molecules

• 11.9 Å rigid spacer

A unique photoreactive crosslinker for carbonyls

• Terminal amine reacts with carbonyls in presence of EDC forming a stable amide bond

• Iodinatable

• HydroxyPhenylAzide reacts with amines upon photolysis

• Can be used too to modify carbonyls too

p-AzidoBenzoyl Hydrazide

MW 177.2

4-(p-AzidoSalicylamido)butylamine

MW 249.3

Applications / Literature

Glycosylated proteins studies

Immunoglobulin conjugates

O’Shannessy (1985), O’Shannessy (1984)

Applications / Literature

Associated product : EDC #UP52005

Hermanson (1996)

1

2

3

4

5

6

7

8

9

10

11

12

13

BACK

211 Bis Avenue Kennedy - BP 1140 - 03103  Montluçon cedex - FRANCE

Tel (33) (0) 4 70 03 88 55 -  Fax (33) (0) 4 70 03 82 60 - uptima@interchim.com  www.interchim.com