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SUPPLIERS > Tosoh Bioscience > TOYOPEARL & TSKgel
TOYOPEARL® and TSKgel® chromatography resins

TOYOPEARL® chromatography resins are hydrophilic, macroporous, bulk processing media designed especially for large-scale chromatography applications. TOYOPEAR®L resins are available for the most common modes of liquid chromatography: size exclusion (SEC), hydrophobic interaction (HIC), ion exchange (IEC) and Affinity chromatography (AFC).

Based on their semi-rigid backbone structure TOYOPEARL® resins assure excellent pressure/flow characteristics. TOYOPEARL® is stable over the pH 2-13 range. Particle sizes are 20-40 µm superfine grade (S) for the highest performance, 40-90 µm for economical purification (M), and 90-120 µm coarse grade (C) and 100 - 300 µm extra coarse grade (EC) for the largest scale chromatography.

Similar Chemistries of TOYOPEARL® and TSKgel® columns allow seamless scale up. TOYOPEARL® polymeric resins are available as bulk resin and in prepacked ToyoScreen® columns for convenient screening.
 
Featured product
TOYOPEARL® AF-rProtein A HC-650F the ultra-high capacity Protein A resin

The new TOYOPEARL® AF-rProtein A HC-650F is designed for high-throughput processing of high titer feedstock. It achieves 30% to 50% greater antibody adsorption than similar products and can considerably improve process economics.
 
HIGHLIGHTS
  • Superior dynamic binding capacity for human IgG (> 70 g/L)
  • Capacity increases with feedstock titers up to 10 g/L and higher
  • Alkaline stability through engineered recombinant ligand
  • Minimized leaching through multi-point attachment
The new Protein A resin is available as bulk material, pre-packed ToyoScreen® column and ToyoScreen® RoboColumnTM for automated resin screening
 
More information on the new  TOYOPEARL® AF-rProtein A HC resin.

 


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