What is BME and how does it work?
FAQ from Trevigen
Cultrex® Basement Membrane Extract (BME) is purified from murine Engelbreth-Holm-Swarm (EHS) sarcoma. BME is composed of soluble basement membrane proteins that gel at 37ºC to form a reconstituted basement membrane. Major components include laminin I, collagen IV, entactin and heparin sulfate proteoglycan. BME can be used for promotion and maintenance of differentiated phenotype in a variety of cell types. The matrix may also be used as a barrier to assess the invasive potential of migrant cells. (Cat# 3430, 3431, 3432, and 3433)