What are the charges on CF™ dyes?
Posted: Thu 11 Dec 2014 20:55What are the charges on CF™ dyes?
FAQ from Biotium
Most CF dyes carry 1-2 negative charges while a few cyanine-based near-IR CF dyes carry 3-4 negative charges. However, the more negatively charged CF dyes comprise unique structural features that shield the negative charges such that the biomolecules (such as antibodies) the dyes label do not lose specificity due to the excessive negative charges.
FAQ from Biotium
Most CF dyes carry 1-2 negative charges while a few cyanine-based near-IR CF dyes carry 3-4 negative charges. However, the more negatively charged CF dyes comprise unique structural features that shield the negative charges such that the biomolecules (such as antibodies) the dyes label do not lose specificity due to the excessive negative charges.