211 bis, avenue J.F. Kennedy - BP 1140 - 03103 Montluçon cedex - France
Hot line (33) (0) 4 70 03 73 06 - Tel. (33) (0) 4 70 03 88 55 - Fax. (33) (0) 4 70 03 82 60
|
Rat monoclonals against Human CD Anti Human CDw41 megakaryocytic lineage |
| Rat IgG2bk - clone LO-CDw41 (LO-PL3b) |
|
Format |
Cat. |
Qty |
|
Purified |
UPB92700 |
0.5ml |
|
Purified |
UPB92701 |
1ml |
|
Biotin |
UPB92710 |
0.5ml |
|
Biotin |
UPB92711 |
1ml |
|
FITC |
UPB92720 |
0.5ml |
|
FITC |
UPB92721 |
1ml |
|
Peroxidase |
UPB92730 |
0.5ml |
|
Peroxidase |
UPB92731 |
1ml |
|
Specifications |
|
Origin : |
Hybridoma derived by hybridization of non secreting rat myeloma IR983F (1) cells with spleen cells of an OkA inbred strain rat immunized against human mononuclear cells and platelets. |
|
Isotype : |
Rat k IgG2a, allotype Igk-1b |
|
Antigen Specificity : |
Platelets glycoprotein complexIIb-IIIa whose subunits have estimated molecular weights of 96, 106 and 26 kDa (2). |
|
Cellular Reactivity : |
Reacts with platelets, bone marrow megakaryocytes. - Does not react with lymphocytes, monocytes,
granulocytes or erythrocytes. |
|
Applications : |
Identification of acute myeloblastic leukemia involving
the megakaryocytic lineage. |
|
References (1) Bazin H. Production of rat monoclonal antibodies with the LOU rat non secreting IR983F myeloma cell line. Prot. Biol. Fluids, 1982, Peeters E. ed., 29th colloquium 1981 Pergamon Press Oxford and N.Y.: 615-618. (2) Ravoet et al. in "Leucocyte Typing III: White Cell Differentiation Antigens" (Mc Michael et al. eds) Oxford University Press, 1987, p 755- 758. (3) Leucocyte Typing IV. White Cell Differentiation Antigens. W. knapp et al. (eds), Oxford University Press, 1989, p. 951, 967, 971, 981. |
|
211 bis, avenue J.F. Kennedy - BP 1140 - 03103 Montluçon cedex - France Hot line (33) (0) 4 70 03 73 06 - Tel. (33) (0) 4 70 03 88 55 - Fax. (33) (0) 4 70 03 82 60 |