What is difference between HybriWell and Secure Seal?
Posted: Wed 11 Feb 2015 18:19What is difference between HybriWell and Secure Seal?
FAQ from Gracebio
Fundamentally, the difference between them is the difference in surface to volume due to the increased depth of the chamber. If you wish to achieve the best active mixing you should select a chamber size in which the fluid moves freely during rotation, facilitated by leaving a small “mixing bubble” within the chamber. SecureSeals use greater fluid volume per surface area compared to HybriWells. For the least amount of volume (to conserve reagents) per surface area, HybriWells are the best choice. Both are recommended for DNA chips, however depending on your choice of reagent and surface modification of the glass, one type of chamber may bond more aggressively than the other, as they use different adhesives.
FAQ from Gracebio
Fundamentally, the difference between them is the difference in surface to volume due to the increased depth of the chamber. If you wish to achieve the best active mixing you should select a chamber size in which the fluid moves freely during rotation, facilitated by leaving a small “mixing bubble” within the chamber. SecureSeals use greater fluid volume per surface area compared to HybriWells. For the least amount of volume (to conserve reagents) per surface area, HybriWells are the best choice. Both are recommended for DNA chips, however depending on your choice of reagent and surface modification of the glass, one type of chamber may bond more aggressively than the other, as they use different adhesives.