Mya 4 Reaction Station, one reaction station with limitless possibilities
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Key Features
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| A 4-zone reaction station offering safe and precise heating, active cooling, software control and data-logging for 24/7 unattended chemistry |
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Overview
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| A flexible tool for a wide range of applications, from discovery chemistry to process development |
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Flexible and versatile
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- 4 different temperature zones, each with heating and active cooling
- Use one compact system for a range of experiments
- Precise temperature control
- Magnetic or optional overhead stirring
- Accepts a wide range of vessel sizes and styles
- Control your experiments and log results automatically
- Use Mya 4 with or without a chiller
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Applications
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- Single or parallel synthesis
- Design of Experiment (DoE)
- Process development
- Scale up
- Route scouting
- Crystallisation studies
- Polymorph screening
- Lead optimisation
- Reaction optimisation
- Reagent, catalyst and solvent screening
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Safer, cleaner, greener and more productive
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- Replace inefficient, messy and unsafe oil and ice baths
- Save space compared with separate reaction set-ups
- Software control improves safety, reduces manual errors, and allows 24/7 unattended chemistry, for improved productivity
- Create, repeat and share experiments and results with ease and accuracy
- Easily manage complex multi-step and multi-device experiments
- Integrate 3rd party devices such as pumps, balances and pH sensors etc.
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Mya 4 - Details
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| Precise temperature control of four independent zones with magnetic or overhead stirring |
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4 reaction zones
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- Use 1, 2, 3 or 4 zones
- Operate zones in parallel or individually by multiple users
- Compact footprint 600 (W) x 360 (D) x 370 (H) mm
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Precise temperature control
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Temperature range from -30 °C to +180 °C (block temperature)
- Providing a solution temperature of at least -20 °C to 150 °C
- Up to 200 °C difference between adjacent positions
- Control the temperature of each zone independently
- Choose to control by block or solution temperature
- Pt100 temperature probes available in stainless steel or PTFE coated
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Use Mya 4 with or without a chiller
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Mya 4 uses powerful Peltier technology to provide rapid cooling to -30 °C
- Peltier cells require tap or chilled water to dissipate heat
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Peltier cooling source |
Tap water at 15 °C |
Chilled water at 5 °C |
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Minimum block temperature |
-25 °C |
-30 °C |
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Minimum solution temperature |
-20 °C |
-25 °C |
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Magnetic or optional overhead stirring
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- Integrated magnetic stirring - from 100 to 1000 rpm
- Optional overhead stirring - from 100 to 1000 rpm
- Control the stirring speed of each position independently
- Use magnetic or overhead stirring in adjacent zones
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Software control and data logging
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Choice of Touch-screen Control Pad and PC Control Software
- Run experiments in manual or profile mode
- Easily repeat profiles
- Export CSV data
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Glassware and accessories
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| Choose from a wide selection of vials, tubes, round bottom flasks and process vessels, from 2 ml to 400 ml |
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Wide selection of vessel styles and volumes
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Vials and tubes from 2 ml to 50 ml:
- 12 mm, 16 mm, 17 mm, 17 mm tapered, 24 mm, 1 inch and 28 mm diameters
- Radleys Carousel 12 Plus reaction tubes
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Round bottom flasks from the Carousel 6 Plus range:
- 25 ml, 50 ml, 100 ml and 250 ml
- One or two side arm options
- Standard and wide neck options
- Baffled vessel options
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Process reaction vessels:
- With straight sides and dished base to mimic jacketed reactors
- 50 ml, 100 ml, 150 ml, 250 ml and 400 ml
- Side arm option
- Baffled vessel options
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Aluminium Inserts
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Removable anodised aluminium inserts for different size vessels
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Multi-neck lids
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| For wide neck round bottom flasks and process vessels |
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Glass lids
- 3 or 5-neck
- 3.3 Borosilicate glass
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PTFE lids
- 5-neck
- For improved durability and safety
- Stronger to support heavier probes/accessories
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Accessory glassware
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A wide range of dedicated glass accessories including:
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- Condensers
- Dropping funnels
- Solid addition funnels
- Stoppers
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Head options - refluxing & glassware support
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| Choose from three different Mya 4 heads to suit your chemistry needs. Easy to set up and no tools required. |
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Manifold Head
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Provides cooling water to glass condensers and distributes inert gas
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- Required when using multi-neck lids
- All the water connections have shut-off valves - no mess
- Note: Glassware with reflux tubes can be used but not for refluxing
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Reflux Head
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Cools reflux tubes and distributes inert gas
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- Can be used with reflux tubes (or wide neck reflux tubes) and short tubes/vials
- Note: Can be used with overhead stirrers
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Support Head
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Choose the Support Head if you want to use different glassware and accessories such as:
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- Findenser and Findenser Mini
- Traditional glass condensers
- Non-standard flasks and tubes
- Soxhlet extraction glassware
- Probes and sensors
- Use with StarFish gas and water manifold
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Customer testimonials
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Accurate temperature control achieving big results, on a small scale
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Mya 4 applications which require accurate temperature control:
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- Exothermic reactions - which require active cooling
- Study of parameters other than temperature - which require reliable and reproducible temperatures
- Working with temperature-sensitive materials (e.g. biomolecules) - which require tightly controlled temperatures
- Experiments requiring slow cooling or heating ramps
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Johnson Matthey - Macfarlan Smith, API manufacturer
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Study of key processing parameters other than temperature
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´The precise temperature control provided by the Mya 4 has been essential to understanding key processing parameters of temperature sensitive experiments. It has allowed us to improve our understanding of current manufacturing processes.´ ´Without accuracy of temperature, you cannot conduct a successful design of experiment (DoE) exercise.´
Dr Timothy Davies, Senior Development Chemist |
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Opioid manufacturer
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Carefully controlled cooling ramps for crystallisation optimisation
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´Prior to acquiring Mya 4, we used stirring hotplates and liquid cooling baths (dry ice/acetone) when needed. The set up and tinkering using this regime was completely obviated with Mya 4, which is basically a walk up reaction workstation.´
´We do a lot of reaction optimisation work (different catalyst loads, different temperatures, etc.) and recently had to do a crystallisation optimisation that required carefully controlled cooling ramps – all of this was a breeze with Mya 4 and made our research progress much quicker.´
Senior Process Development Chemist |
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Purolite Life Sciences, Resin manufacturer
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Temperature-sensitive materials and exothermic reactions
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´Mya 4 fulfils the need of a multipurpose small-scale reactor system that is not overspecified. The fact that the unit is so versatile is a strong advantage.´
´On previous systems I have looked at, flask sizes were limited to only one or two options.
I would have loved a Mya 4, two years ago so I could have used it as the workhorse for most of the project.´
Dr Patrick Gilbert, R&D Manager |
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Mya 4 Control Pad
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Unattended chemistry 24/7 with software control for improved productivity, safety and reduced manual errors
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Touch-screen Control Pad
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- Supplied as standard with Mya 4
- Set automated profiles or use manual control
- Intuitive and easy to use
- Compact footprint
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Control Options
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The touch-screen Control Pad requires minimal training. It will control and log heating/cooling and stirring for all four zones independently. Repeating experiments and exporting data is a breeze.
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Upgrade to the Mya 4 PC Control Software if you also want to:
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- Integrate 3rd party devices e.g. pumps and pH meters
- Create profile experiments with any number of steps
- Increase safety by using warnings, safe states and shut down settings
- Create a comprehensive report in a few clicks at the end of your experiment
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| Features |
Control Pad |
PC Software |
| Intuitive and easy to use touch-screen control |
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| Compact footprint - fumehood compatible |
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| Maximum 10 steps of 16 hours each |
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| Multi-user - independently run experiment in 4 zones |
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| Control and log the temperature and stirring of each zone independently |
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| Set safety limits |
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| Export experimental profiles and results in CSV via USB memory stick |
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| Adjust parameters manually - using manual/direct mode |
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| Create multi-step recipes - using profile/schedule mode |
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| Flexibility to make and track on-the-fly adjustments to your experiment |
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| Automatically log all data |
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| Share experimental results and recipes with other users |
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| View real-time graphs |
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| Control and log up to 16 x 3rd party devices on one screen |
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| Create complex experiments with any number of steps |
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| Interlink devices and set feedback/control loops and end point conditions |
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| Report Wizard creates detailed reports in RTF or export results in CSV |
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| Log comments |
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| Runs on a Windows laptop |
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Mya 4 PC Control Software will control and log 3rd party devices
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Control 3rd party devices
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Mya 4 Control Software includes a library of pre-configured driver files allowing easy integration with a range of 3rd party devices.
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Data hub
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Using the Data Hub, Mya 4 Control Software can connect to, control and log data from multiple devices with an RS232 serial interface. |
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How to configure your Mya 4 Reaction Station
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| Select the components you need to suit your chemistry Our experts can advise you on the best options for your application |
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Stirring options
Select stirrer bars for magnetic stirring and/or Mya compact stirrers and stirrer shafts for overhead stirring. |
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Head options
Select a Manifold, Reflux or Support head. |
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Lids or reflux tubes
Glass or PTFE multi-neck lids. Standard or wide-neck reflux tubes. |
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Vessel styles & volumes
Select vessels: tubes, vials, round bottom flasks and process vessels from 2 ml to 400 ml. |
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Aluminium inserts
Select the appropriate insert for each vessel size.
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Select accessories
Temperature probes, funnels, condensers etc. |
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Control options
Select the optional Mya 4 PC Control Software, Data Hub and any 3rd party devices. |
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Mix & Match
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| A flexible reaction station with a wide range of options and accessories to fit your needs |
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Reflux Head
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Manifold Head
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Applications
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- Single or parallel synthesis
- Design of Experiment (DoE)
- Process development
- Scale up
- Route scouting
- Crystallisation studies
- Polymorph screening
- Lead optimisation
- Reaction optimisation
- Reagent, catalyst and
solvent screening
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